Late Show with David Letterman S13E51 · George Clooney, Ashlee Simpson

Late Show with David Letterman

Season 13 · Episode 51 · George Clooney, Ashlee Simpson

Dave shocks the audience with the news that Oprah Winfrey will be a guest on the show a week from Thursday; Biff undergoes Lasek eye surgery; George Clooney promotes "Syriana."